Dedicated hosting server providers utilize extreme security measures to ensure the safety of data stored on their network of servers. Providers will often deploy various software programs for scanning systems and networks for obtrusive invaders, spammers, hackers, and other harmful problems such as Trojans, worms, and crashers (Sending multiple connections). Linux and Windows use different software for security protection.
Your next major concern will be compatibility. It's not a shock that most businesses run on Microsoft Windows and use some form of Microsoft Office. Being able to use common third-party clients such as Microsoft Outlook can often be a concern, and even today, compatibility with Microsoft Outlook isn't necessarily guaranteed. This is especially true when sending and receiving meeting invites. It only takes one garbled meeting invite to realize how frustrating this can be in the real world. Even if using Microsoft Outlook isn't a concern, portability is. If the service is entirely web-based, then is there a means for me to take my email offline and send email when I connect?